Opiate Withdrawal Symptoms
Opiate withdrawal symptoms are a set of recognizable signs brought about by abrupt cessation or rapid taper from opiates for any person who is physically dependent to opiates.
The most obvious opiate withdrawal symptoms are physical in nature however significant psychological side-effects such as depression and anxiety may be as serious or worse and must be an integrated part of the overall opiate treatment program.
Opiate withdrawal symptoms will appear shortly after discontinuation with opiates like heroin because heroin has a short elimination half-life (6.4 hours). This means that approximately six and one-half hours after last heroin use, 50% of the administered diacetylmorphine (heroin) will be fully metabolized. On the other hand significant opiate withdrawal symptoms will appear much later with opiates like methadone which have a much longer elimination half-life (approximately 24 hours).
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